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Ith the hope of improving responses, impacting survival, and ultimately curing cll. Important agents being tested are targeted on cll surface molecules and their ligands, signal transduction protein and oncogenes. This review provides a brief summary of the recent advances made in preclinical and clinical investigation of selected promising therapeutic agents, which lead the target-directed therapeutic approach. Keywords: cll, akt inhibitors, bcl-2 inhibitors, cyclin d kinase inhibitors, heat shock protein inhibitors, immunomodulatory drugs, monoclonal antibodies post to: cannotea citeulike del. Icio. Us facebook linkedin twitter readers of this article also read: applications of gold nanoparticles in cancer nanotechnology role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors ctla-4 blockade: therapeutic potential in cancer treatments anti-angiogenesis therapies: their potential in cancer management current and emerging therapies for the treatment of pancreatic cancer the spectrum of use of rituximab in chronic lymphocytic leukemia amino acid-responsive crohn's disease: a case study amino acid management of parkinson’s disease: a case study radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in alzheimer disease targeted agents for the treatment of metastatic melanoma have an opinion about one of our articles? We encourage you to write a letter to the editor testimonials "... I was impressed at the rapidity of publication from submission to final acceptance. " dr edwin thrower, phd, yale university intranet access to all dove journals if you would like your institutional intranet to have access to the dove medical press journals please contact me. viagra online viagra online cheap viagra buy viagra online canada no prescription cheap generic viagra buy generic viagra viagra generic discount viagra for sale cheap viagra online Most viewed papers epigenomics in cancer management intercellular cancer collisions generate an ejected crystal comet tail effect with fractal interface embryoid body reassembly transformation topotecan in the treatment of relapsed small cell lung cancer role of trabectedin in the treatment of soft tissue sarcoma search for more articles in the.